Chondrocalcinosis And Osteoarthritis

Chondrocalcinosis - an overview | ScienceDirect Topics

Included in this category are asymptomatic chondrocalcinosis, acute monoarthritis (pseudogout), and clinical presentations mimicking OA (pseudo-osteoarthritis), rheumatoid arthritis (pseudorheumatoid arthritis), and neuropathic joint disease. In CPPD, inflammation is induced by the presence of crystals of calcium pyrophosphate in the joints.

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Chondrocalcinosis and osteoarthritis Archives - ACR ...

Abstract Number: 878 • 2019 ACR/ARP Annual Meeting. The Association of Serum Magnesium with Chondrocalcinosis and Osteoarthritis. Devyani Misra 1, Xianbang Sun 2, Michael Nevitt 3, Beth Lewis 4, James Torner 5, Tuhina Neogi 2, Alice Lichtenstein 6, Nirupa Matthan 6 and David Felson 7, 1 Beth Israel Deaconess Medical Center, Waban, MA, 2 Boston University School of Medicine, Boston, MA, 3 ...

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Analysis of the association between chondrocalcinosis and ...

The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: the Framingham Study. J Rheumatol. 1989 Sep; 16 (9):1241–1245. Sanmartí R, Pañella D, Brancós MA, Canela J, Collado A, Brugués J. Prevalence of articular chondrocalcinosis in elderly subjects in a rural area of Catalonia.

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An ultrastructural study of articular chondrocalcinosis in ...

A study was made by transmission electron microscopy of tissue specimens (cartilage, meniscus and synovial membrane) taken from 5 knees presenting radiological and anatomical signs of articular chondrocalcinosis and osteoarthritis. It was part of a broader study which included analysis of the same specimens by macroscopy and light microscopy as well as by X-ray diffraction of the mineral …

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The Association of Serum Magnesium with Chondrocalcinosis ...

Background/Purpose: High serum magnesium (Mg) may have anti-inflammatory effects and prevents the release of extracellular pyrophosphate, inhibiting CPP deposition. Cross-sectional data has linked low serum Mg levels with radiographic chondrocalcinosis (CC) but there is a paucity of longitudinal studies and an absence of studies of symptomatic CC. Since osteoarthritis (OA) and CC often co ...

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Osteoarthritis Chondrocalcinosis, osteophytes and ...

chondrocalcinosis: evidence that correlation with osteoarthritis is through a shared association with osteophyte. Ann Rheum Dis 2003;62:513. 7 Fam A, Morava-Protence I, Purcell C, Young B, Bunring P, Lewis A. Acceleration of experimental lapine osteoarthritis by calcium pyrophosphate microcrystalline synovitis. Arthritis Rheum 1995;38:201–10.

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Chondrocalcinosis - Wikipedia

Chondrocalcinosis or cartilage calcification is calcification (accumulation of calcium salts) in hyaline cartilage and/or fibrocartilage. It can be seen on radiography.. Causes. Buildup of calcium phosphate in the ankle joints has been found in about 50% of the general population, and may be associated with osteoarthritis.. Another common cause of chondrocalcinosis is calcium pyrophosphate ...

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Chondrocytes From Osteoarthritic and Chondrocalcinosis ...

Apr 26, 2021· The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case-control study. Arthritis Res. Ther. 16 : R25 . 10.1038/nrrheum.2010.182 [ Europe PMC free article ] [ Abstract ] [ CrossRef ] [ Google Scholar ]

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Osteoarthritis andarticular chondrocalcinosis in the elderly

Osteoarthritis andarticular chondrocalcinosis in the elderly 281 60 50-40. 30-z 20-10 0Chondrocalcinosis TOTAL MALE TOTAL MALE TOTAL MALE 1 65 to 74yrs 75 to 84ytrs 85 to 94yrs AGE IN DECADES Fig. 1 Prevalence ofarticularchondrocalcinosis. clinical data, and by the clinicians. Agreement on grading, after the initial ...

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Does Chondrocalcinosis Associate With a Distinct ...

Jul 20, 2015· INTRODUCTION. Osteoarthritis (OA) associates with chondrocalcinosis (CC), which predominantly results from calcium pyrophosphate crystal deposition (CPPD), although basic calcium phosphate (BCP) crystals may coexist 1-3.The association between OA and CC has been confirmed in several independent populations 1, 4, 5, and CC also modifies the distribution of joints affected by OA …

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Does Primary or Secondary Chondrocalcinosis Influence Long ...

Coexistence of degenerative arthritis and calcium pyrophosphate dihydrate (CPPD) crystals (or radiological chondrocalcinosis) with osteoarthritis (OA) of the knees is frequent at the time of arthroplasty. Several studies suggest more rapid clinical and …

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Pseudogout - Symptoms and causes - Mayo Clinic

Jul 16, 2020· Pseudogout (SOO-doe-gout) is a form of arthritis characterized by sudden, painful swelling in one or more of your joints. These episodes can last for days or weeks. The most commonly affected joint is the knee. Also called calcium pyrophosphate deposition disease or CPPD, the common term "pseudogout" was coined for the condition's similarity to ...

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Calcium Pyrophosphate Arthritis - Musculoskeletal and ...

Diagnosis of calcium pyrophosphate arthritis is established by identifying rhomboid- or rod-shaped crystals in synovial fluid that are not birefringent or are weakly positively birefringent on polarized light microscopy. Joint fluid in acute flares has findings typical of inflammation; thus, coincident infectious arthritis and gout (other common causes of inflammatory joint fluid) must also be ...

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Symptoms and Treatments of Chondrocalcinosis - Facty Health

Jan 02, 2019· Chondrocalcinosis is the streaking of ones soft tissues with calcium. Advertisement. Symptoms and Treatments of Chondrocalcinosis. Home Ailments Gout. By Chris, Facty Staff Updated: Jan 2, 2019. 2. Other Symptoms - Osteoarthritis Patients may experience symptoms of osteoarthritis. Osteoarthritis is the degeneration of joints following a ...

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Chondrocalcinosis of the Knee and the Risk of ...

Dec 05, 2019· To assess the impact of knee chondrocalcinosis (CC) on the 5‐year risk of joint replacement and disease progression in patients with knee osteoarthritis (OA).

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Calcium pyrophosphate dihydrate crystal deposition disease ...

Chondrocalcinosis, on the other hand, refers to the radiographic evidence of calcification in hyaline and/or fibrocartilage. "Osteoarthritis (OA) with CPPD" reflects a situation where osteoarthritis features are the most apparent. Pyrophosphate arthropathy refers to several of these situations. References

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Pseudogout | Calcium Pyrophosphate Deposition | Symptoms ...

Oct 10, 2018· This is known as chondrocalcinosis. It may cause no symptoms but may be picked up on an X-ray. Other people may have an attack of joint pain and swelling identical to gout. This is called pseudogout, or acute CPP crystal arthritis. There is also a longer-term condition called chronic CPP crystal inflammatory arthritis.

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Osteoarthritis and articular chondrocalcinosis in the elderly

One hundred consecutive admissions to an acute geriatric unit were examined for clinical and radiographic evidence of osteoarthritis (OA) and articular chondrocalcinosis (ACC). Thirty-four patients had ACC. This was age related, the prevalence rising from 15% in …

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Chondrocytes From Osteoarthritic and Chondrocalcinosis ...

Apr 26, 2021· Basic calcium phosphate (BCP)-based calcification of cartilage is a common finding during osteoarthritis (OA) and is directly linked to the severity of the disease and hypertrophic differentiation of chondrocytes. Chondrocalcinosis (CC) is associated with calcium pyrophosphate dihydrate (CPPD) deposition disease in the joint inducing OA-like symptoms.

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Association between chondrocalcinosis and osteoarthritis ...

Aim: To systematically examine the existing literature on the associations between chondrocalcinosis (CC) and osteoarthritis (OA) at different joints, and to quantify such associations through meta-analysis. Methods: PubMed, Embase and Scopus databases were searched through from inception to June 2017. Cohort, case-control or cross-sectional studies were included if they examined the ...

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Chondrocalcinosis 2 | Genetic and Rare Diseases ...

Jan 12, 2018· Chondrocalcinosis 2 is a rare disease characterized by the accumulation of calcium pyrophosphate dihydrate (CPP) crystals in and around the joints.A buildup of these crystals can lead to joint pain and damage that is progressive (worsens over time). Signs and symptoms of the disease include chronic joint pain or sudden, recurrent episodes of pain, as well as stiffness or swelling of the …

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Prevalence of rheumatoid arthritis, osteoarthritis ...

Prevalence of rheumatoid arthritis, osteoarthritis, chondrocalcinosis and gouty arthritis at age 79. Bergström G, Bjelle A, Sorensen LB, Sundh V, Svanborg A. The prevalence of rheumatic diseases was studied in representative subsamples by interview (n = 134), and by physical (n = 89) and radiographic (n = 81) examination in a representative ...

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Analysis of the association between chondrocalcinosis and ...

Jan 01, 1996· The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: the Framingham Study. J Rheumatol. 1989 Sep; 16 (9):1241–1245. [Google Scholar] Sanmartí R, Pañella D, Brancós MA, Canela J, Collado A, Brugués J. Prevalence of articular chondrocalcinosis in elderly subjects in a rural area of Catalonia.

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Chondrocalcinosis: Overview and More

Nov 15, 2012· Chondrocalcinosis is a rheumatologic condition that is characterized by accumulation of calcium pyrophosphate dihydrate crystals or CPPD crystals in connective tissues or the joint cartilages. The disease is often associated with similar conditions such as osteoarthritis, pseudogout and pseudo-osteoarthritis.

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Chondrocytes From Osteoarthritic and Chondrocalcinosis ...

Apr 26, 2021· Chondrocalcinosis (CC) cartilage shows less severe histological cartilage destruction. (A) Representative images for the tibial plateau of healthy controls, as well as osteoarthritis (OA) and CC patients (the black square indicates the main loading area and region of sampling).

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A Gene May Induce Chondrocalcinosis and Osteoarthritis

Aug 11, 2000· Comment. The ank gene very likely plays a role in familial and other forms of chondrocalcinosis; what role it plays in osteoarthritis is unclear. Because about half of all cases of osteoarthritis are thought to involve genetic vulnerability, the discovery of this gene, along with the recent discovery of the osteoprotegerin gene (see JW Dec 15 1999, p. 192, accession number …

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Arthritis News : Is Knee Chondrocalcinosis Associated with ...

Apr 26, 2007· A strong association between chondrocalcinosis, resulting from calcium pyrophosphate dihydrate (CPPD) deposition, and knee osteoarthritis (OA) is firmly established. However, despite the association, a causative pathogenic role for CPPD crystals on the progression of articular degeneration in the knee has not been definitively demonstrated.

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Chondrocalcinosis - OrthopaedicsOne Review - OrthopaedicsOne

Chronic chondrocalcinosis is usually asymptomatic, but may lead to poly-articular osteoarthritis; X-Rays: Calcification of articular cartilage and fibro-cartilaginous structures (menisci, TFCC, symphysis pubis, intervertebral discs) Punctate, or linear densities in articular hyaline cartilage or fibro-cartilage

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